IGF-1 LR3 1000mcg – Apoxar
IGF-1 LR3 (Insulin-Like Growth Factor-1 Long R3) – Compound Profile
is a modified version of the naturally occurring Insulin-Like Growth Factor-1 (IGF-1). It has been engineered for enhanced stability, potency, and bioavailability, making it a popular choice among athletes and bodybuilders for its muscle growth and recovery benefits. Apoxar IGF-1 LR3 1000mcg refers to a high-quality, research-grade peptide commonly sold in lyophilized (powder) form for reconstitution.
Key Features of IGF-1 LR3
- Extended Half-Life:
- Unlike native IGF-1 (half-life: ~20–30 minutes), IGF-1 LR3 has a significantly extended half-life of ~20–30 hours, enabling once-daily administration.
- Enhanced Binding Properties:
- Modified to avoid binding to IGF-binding proteins (IGFBPs), allowing more active IGF-1 to circulate in the bloodstream and exert its effects.
- Anabolic Potency:
- Promotes muscle hypertrophy, cell growth, and repair.
- Potentiates the effects of growth hormone (GH).
Mechanism of Action
IGF-1 LR3 mimics the actions of natural IGF-1 by binding to IGF-1 receptors in muscle, bone, and connective tissues. This activation leads to:
- Protein Synthesis: Promotes muscle growth and recovery.
- Cellular Proliferation: Stimulates cell division and repair in various tissues.
- Nutrient Partitioning: Directs glucose and amino acids into muscle cells for growth.
Benefits of IGF-1 LR3
- Muscle Growth:
- Enhances lean muscle tissue growth by increasing protein synthesis and satellite cell activation.
- Fat Loss:
- Improves insulin sensitivity and promotes fat oxidation, making it ideal for body recomposition.
- Improved Recovery:
- Speeds up recovery from intense workouts by repairing muscle fibers and reducing inflammation.
- Anti-Aging Effects:
- Supports skin elasticity, bone density, and overall tissue health.
- Joint and Tendon Repair:
- Promotes healing of connective tissues, reducing injury risk.
Dosage and Administration
- Standard Dosage:
- 20–50 mcg/day, depending on individual goals and tolerance.
- Some advanced users may go up to 100 mcg/day, but this is less common.
- Injection Timing:
- Administer subcutaneously (SC) or intramuscularly (IM) in the morning or post-workout for optimal results.
- Cycle Duration:
- Typically used for 4–6 weeks, followed by an equal time off to avoid desensitization.
Reconstitution and Storage
- Reconstitution:
- Mix the 1000mcg (1mg) vial of IGF-1 LR3 with bacteriostatic water or sterile water.
- For example, if reconstituting with 1 mL of bacteriostatic water, the concentration will be 1000 mcg/mL (1 mcg/μL).
- Storage:
- Lyophilized Powder: Store in a cool, dry place (e.g., refrigerator) before reconstitution.
- After Reconstitution: Store in the refrigerator (2–8°C) and use within 20–30 days.
Potential Side Effects
While IGF-1 LR3 is generally well-tolerated, some users may experience side effects, including:
- Common:
- Hypoglycemia (low blood sugar): IGF-1 enhances insulin sensitivity.
- Localized swelling or irritation at the injection site.
- Less Common:
- Headaches.
- Joint pain (related to rapid growth or repair).
- Mild water retention.
- Rare:
- Excessive growth of tissues (e.g., organs or cartilage) if abused.
- Insulin resistance with long-term or high-dose use.
Stacking Protocols
IGF-1 LR3 is often used alongside other compounds for enhanced results:
- With Growth Hormone (GH):
- Amplifies the anabolic effects of GH by increasing IGF-1 levels systemically.
- With Anabolic Steroids:
- Synergizes with steroids like Testosterone or Nandrolone for rapid muscle growth.
- With Peptides:
- Combined with GHRP-6 or CJC-1295 to boost growth hormone release and enhance recovery.
Safety and Monitoring
- Monitoring:
- Regular blood glucose checks to avoid hypoglycemia.
- Periodic blood tests to assess IGF-1 levels and ensure safety.
- Avoiding Desensitization:
- Do not exceed recommended cycles or doses to prevent receptor downregulation.
Legal and Research Considerations
- Research Status:
- IGF-1 LR3 is classified as a research peptide and is not FDA-approved for therapeutic use.
- Legal Use:
- Availability may vary depending on regional regulations; ensure compliance with local laws.
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