MOTS-C (10mg)

MOTS-C 10mg refers to a synthetic form of a mitochondrial-derived peptide called MOTS-c, typically administered at a 10 mg dose, often for its potential role in metabolic regulation, aging, and exercise performance enhancement.  has gained interest in the fields of anti-aging, metabolic health, and athletic optimization.

What is MOTS-c?

• MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a peptide naturally encoded in the mitochondrial genome.
• It plays a role in cellular energy regulation, metabolic homeostasis, and stress adaptation by influencing how mitochondria respond to metabolic stress.
• MOTS-c mimics and enhances processes associated with exercise and metabolic flexibility.

Mechanism of Action

1. Metabolic Regulation:
   • Enhances glucose uptake in muscle cells independent of insulin.
   • Regulates metabolic pathways, including AMPK activation, which supports energy balance and fat oxidation.
   • May counteract metabolic dysfunctions associated with aging or obesity.
2. Stress Resistance:
   • Increases mitochondrial function and resilience to oxidative stress.
   • Promotes adaptive cellular responses to environmental or physiological stressors.
3. Exercise Mimetic:
   • MOTS-c has been shown to mimic some of the benefits of exercise, including improved endurance and enhanced energy utilization in cells.

Potential Benefits (10mg Dose)

1. Metabolic Health:
   • May improve insulin sensitivity and blood glucose regulation.
   • Potential to address obesity, prediabetes, or type 2 diabetes.
2. Aging:
   • Regulates mitochondrial function, potentially delaying age-related metabolic decline.
   • Enhances resilience to age-associated stressors and may increase lifespan (as suggested by preclinical studies).
3. Performance Enhancement:
   • Could boost energy production and endurance in athletes or individuals seeking physical performance improvements.
4. Weight Management:
   • By increasing metabolic flexibility, MOTS-c might aid in weight control and fat loss.

Administration (10mg)

• Typically delivered as a subcutaneous injection (once daily or based on protocol).
• Research and clinical applications often utilize 10 mg as a standard dose for experimental or therapeutic purposes.